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药学(337)

姓名:李**

性别:男

国籍:韩国

联系电话:0631-5651499

E-Mail:xinhanrc@163.com

教育经历

1983年2月毕业于庆熙大学药学系(药学学士)
1985年2月毕业于庆熙大学研究生院(药学硕士)
1991年毕业于Katholike University Leuven医学院(医学博士)
 

研究方向

抗癌及抗炎功效搜索、机制研究及药物开发
 
• 免疫增强功效搜索、机制研究及药物开发
 
• 抗皮肤老化功效搜索、机制研究及药物开发
 
• 噬菌体多聚化调节机制研究
 
• 炎症性疾病与microbiota相关性研究
 
• 生物等效性试验(食药处认证机构药物分析及CYP等DDI调节机制)
 
• 药理活性搜索、机制研究及目标发掘和药物开发(皮肤老化及保湿、肥胖)
 
• 开发出以mPGES-1为目标的关节炎治疗剂
 

主要成果

Immunostimulatory effects of cordycepin‐enriched WIB‐801CE from Cordyceps militaris in splenocytes and cyclophosphamide‐induced immunosuppressed mice
 
Phytotherapy Research 2018;32:132–139
 
9-Hydroxycanthin-6-one isolated from stem bark of Ailanthus altissima induces ovarian cancer cell apoptosis and inhibits the activation of tumor-associated macrophages.
 
Chemico-Biological Interactions 280 (2018) 99–108
 
Iloprost, a prostacyclin analog, inhibits the invasion of ovarian cancer cells by downregulating matrix metallopeptidase-2 (MMP-2) through the IP-dependent pathway
 
Prostaglandins and Other Lipid Mediators 134 (2018) 47–56
 
Asymmetric dimethylarginine (ADMA) is identified as a potential biomarker of insulin resistance in skeletal muscle
 
Scientific Reports (2018) 8:2133
 
Kaempferol 7-O-β-D-glucoside isolated from the leaves of Cudrania tricuspidata inhibits LPS-induced expression of pro-inflammatory mediators through inactivation of NF-κB, AP-1, and JAK-STAT in RAW 264.7 macrophages
 
Chemico-Biological Interactions 284 (2018) 101–111
 
; 等  60多篇