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药学(332)

姓名:朴**

性别:男

国籍:韩国

联系电话:0631-5651499

E-Mail:xinhanrc@163.com

教育经历

1981年,首尔大学(药学学士)
1983年,首尔大学(医学硕士-药物化学)
1995年,美国堪萨斯大学(医学化学博士)
 
 

研究方向

药物设计
生物活性玉米磅的结构-活性、关系研究
不对称合成
综合方法的发展
抗炎药
 

主要成果

代表论文
 
Highly Stereoselective Asymmetric Total Synthesis of (-)-Jimenezin via Sequential Intramolecular Amide Enolate Alkylation
 
Synthesis of Halogenated 1,5-Diarylimidazoles and Their Inhibitory Effects on LPS-Induced PGE(2) Production in RAW 264.7 Cells
 
Interruption of Helicobacter pylori-Induced NLRP3 Inflammasome Activation by Chalcone Derivatives

Synthesis, in vitro evaluation, and computational simulations studies of 1,2,3-triazole analogues as DPP-4 inhibitors
 
Cross-Metathesis of Methallyl Halides: Concise Enantioselective Formal Total Synthesis of (?)-Presphaerene
 
Stereoselective Protection-Free Asymmetric Total Synthesis of (+)-Chamuvarinin, a Potent Anticancer and Antitrypanosomal Agent: Substrate-Controlled Construction of the Adjacently Linked Oxatricyclic Core by Internal Alkylation
 
 
Flavonoids interfere with NLRP3 inflammasome activation
 

Inhibitory activity of Cordyceps bassiana extract on LPS-induced inflammation in RAW 264.7 cells by suppressing NF-κB activation